Confocal and multiphoton microscopes are standard fare in academic imaging facilities, but ultrahigh-resolution systems generally have a smaller user base – namely, their inventors. Soon facilities ...

The 4Pi Confocal Laser Scanning Microscope is the world's most advanced optical microscope--capable of revealing the nanostructure of genetic material within a cell in three dimensions. Bar Harbor ...

The three to seven fold improved axial resolution provided by 4Pi microscopy 1,2,3 in the 1990s marked a first step in the quest for radically improving the resolution in far-field fluorescence ...

Functional principle of the STED-4Pi-Microcope: The interference of both red light pulses to a common focal point and the fluorescent excitation through the STED feeds the fluorescent point along the ...

Proteins called H2AX act as "first aid" to DNA, among other roles. For the first time, scientists using the world's most powerful light microscope (the only one of its kind in the Americas) have seen ...

Bar Harbor, Maine–The 4Pi Confocal Laser Scanning Microscope is the world's most advanced optical microscope--capable of revealing the nanostructure of genetic material within a cell in three ...