TRAFs (tumour-necrosis factor receptor (TNFR)-associated factors) have multiple roles in B-cell biology. These include involvement in cellular activation, differentiation and the apoptotic signals ...
CD40, a member of tumour necrosis factor receptor (TNFR) superfamily, has a pivotal role in B-cell-mediated immunity through various effector pathways including AKT kinase, but the signal transduction ...
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