A once-promising Colts season that included a 7-1 start, has ended without a postseason berth, sparked by a historic late-season collapse.

Trevor Lawrence ran for two scores, Cam Little kicked a tiebreaking 42-yard field goal with 6:58 left, and the Jacksonville Jaguars beat the Indianapolis

Notable odds: The Bears secured a playoff berth via the Lions' loss to the Steelers in Week 16, and they won the NFC North after their overtime win over the Green Bay Packers, who also fell to the Ravens on Saturday night. The Bears also have about a 14% chance at the No. 1 overall seed.

The San Francisco 49ers offense is cruising and they were dominant in a win over the Indianapolis Colts. Here are the highlights.

Following yet another loss, the Indianapolis Colts dropped -- just a bit -- in the latest Week 18 NFL power rankings. The Colts ' 23-17 loss to the Jacksonville Jaguars this past Sunday was the team's sixth in a row. Before kickoff of that game even took place, the Colts were eliminated from playoff contention after a Houston win.

Week 16 wraps up with one playoff team and one playoff hopeful. The Niners are rising; the Colts are desperate.

The Jacksonville Jaguars won their seventh game in a row, but they dropped in the latest Week 18 power rankings.

NFL Week 18 odds, picks, predictions, TV channel, streaming information for the Sunday football game between Indianapolis Colts and Houston Texans.