Despite being an essential developmental process, the understanding of human embryonic genome activation is limited, owing to the lack of in vitro cell models and ethical concerns. To advance ...

Under the microscope, MSK scientists studied how cells in a mouse embryo (green) move out and break away from their original tissue by contracting their surfaces (red). Studying this process, known as ...

Long before human bone marrow takes over the task of producing blood, discrete waves of blood cell production occur in the developing embryo. Miriana Dardano, a postdoctoral researcher in Zweigerdt’s ...

Embryonic development is a meticulously orchestrated process in which spatial and temporal cues guide cell fate determination and tissue patterning. Central to this process is morphogen signalling – a ...

Researchers have discovered a key transition in early embryonic development is facilitated by decreasing levels of a viral protein inserted into the DNA of our early animal ancestors. Researchers at ...

A research team showed that, contrary to current models, one early embryonic cell dominates lineages that will become the fetus. “They are not identical,” said Magdalena Zernicka-Goetz, a ...

Researchers have published an atlas of zebrafish development, detailing the gene expression programs that are activated within nearly every cell type during the first five days of development, a ...

A platform approach to bioprocessing uses the same set of protocols and systems found during early phase development. Scientists then transfer the protocols, by either scaling-up or scaling-out, ...

Chromosphaera perkinsii is a single-celled species discovered in 2017 in marine sediments around Hawaii. The first signs of its presence on Earth have been dated at over a billion years, well before ...