Several members of the NLR family of sensors activate innate immunity. In contrast, we found here that NLRC3 inhibited Toll-like receptor (TLR)-dependent activation of the transcription factor NF-κB ...
The acetyltransferase HAT1 moderates the NF-κB response by regulating the transcription factor PLZF
Post-translational modifications of amino acids are critical to regulate enzyme activity. Of the numerous covalent modifications, the consequence of protein phosphorylation has been most prominent and ...
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