Adopting a Quality by Design (QbD) approach for wet granulation requires manufacturers to comprehend the correlation between process variables, such as powder characteristics and equipment ...

The authors prepared granules containing cinnarizine using polyethylene glycol 6000 as a melting binder and lactose monohydrate as hydrophilic filler. The effects of binder concentration and size were ...

Use of in-process particle size analysis has enabled pharmaceutical scientists and process engineers to track the progress of a granulation process and detect its endpoint. Alon Vaisman. Applications ...

Dry granulation, also called roller compaction, has been a popular method in recent years and has many applications. The powder is compressed between revolving rollers to generate flakes. The flakes ...