This important study provides a mechanistic view of how antibody affinity maturation can reshape encounter-state landscapes and association pathways, with implications for understanding HIV antibody ...
Abstract: Balancing optimality and robustness is the key to solving expensive robust multiobjective optimization problems (ExRMOPs) by evolutionary algorithms. However, existing studies usually design ...
Abstract: Most existing studies in dynamic multi-objective optimization (DMO) focus on tracking changing Pareto optimal sets and/or the entire Pareto-optimal fronts (PFs). However, there may be ...
With the recent Nobel Prize awarded for radical advances in protein discovery, foundation models (FMs) for exploring large combinatorial spaces promise to revolutionize many scientific fields.
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