Craig Morgan outlines why comparator clinical trials are useful and provides points to consider to ensure the best outcome. In clinical trials, a comparator drug (defined as ‘an investigational or ...

Despite randomised clinical trials (RCTs) being the gold standard for drug approval studies, the shift towards precision medicine has increased the use of single-arm trials (SATs). SATs lack results ...

Abstract: A fully-integrated 18.5 kHz RC time-constant-based oscillator is designed in 65 nm CMOS for sleep-mode timers in wireless sensors. A comparator offset cancellation scheme achieves 4× to 25× ...

Abstract: Integrated low-frequency oscillators can replace crystal oscillators as sleep-mode timers to reduce the size and cost of wireless sensors [1]. Since the timer is one of the few continuously ...