Several studies have shown that array based comparative genomic hybridisation (CGH) is a powerful tool for the detection of copy number changes in the genome of individuals with a congenital disorder.
Dr A R Brothman, University of Utah CGH Microarray Laboratory, SOM 1C210, 30N 1900 E, Salt Lake City, UT 84132, USA; art.brothman{at}genetics.utah.edu Purpose: The University of Utah Comparative ...
Abstract: Array comparative genomic hybridization (cgh) is a microarray technology for measuring the relative copy number of thousands of genomic regions. Visual examination of cgh profiles shows that ...
Purpose: To develop a high resolution microarray based method to detect single- and multiexons gene deletions and duplications. Methods: We have developed a high-resolution comparative genomic ...
Introduction: Silver–Russell syndrome (SRS) is an imprinting disorder primarily caused by genetic and epigenetic aberrations on chromosomes 11 and 7. SRS is a rare growth retardation disorder often ...
Edited by Carlo M. Croce, The Ohio State University, Columbus, Ohio, and approved October 17, 2016 (received for review July 23, 2016) Here, we hypothesized and tested whether, in addition to the ...
Neuroblastoma, the most common extracranial malignant solid tumor in childhood has a very diverse clinical behaviour: from spontaneous regression to a very aggressive malignant progression and ...
There is convincing evidence suggesting a potential benefit of chromosomal microarray analysis for fetal abnormalities beyond conventional fetal karyotyping 1 1. Le Caignec C, Boceno M, Saugier-Veber ...
Abstract: Estimation of the genome copy number variations (CNVs) measured using the high-resolution array-comparative genomic hybridization (HR-CGH) microarray is provided in the presence of large ...
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